Degree in Medical
Biotechnology - University of Bologna
ADVANCED
HUMAN GENETICS (I.C.)
Module
of CLASSICAL AND NEXT-GENERATION GENOMICS
- A.Y. 2025/2026
Teacher: Pierluigi Strippoli
Teaching Material 2025/2026 in Virtuale
Paper vs. Pixels
1.
Human Genomics
2. Bibliographic
Databases
3. Nucleic Acid Extraction
4. Nucleic
Acid
Hybridization -
Concept of Probe
Specificity - Southern
Blot - Northern
Blot -
Microarray
5.
Polymerase
Chain Reaction
(PCR)
- Primer design [Example
Article] -
PCR discovery,
PCR plateau -
data, PCR
Review
6. Genetic
Libraries - RNA
Vaccine
7. Nucleic
Acid
Sequencing and Sequence
Analysis
8. System
Biology -
The case of
trisomy 21: a
model for
integrated
research
FILMOGRAPHY
Ron Howard
(Director). Apollo
13.
With Tom Hanks,
Ed Harris. USA,
1995.
["Houston, we
have a problem".
A true story.
The positive
hypothesis when
dealing with a
problem].
George
Miller
(Director). Lorenzo's
Oil.
With Nick Nolte,
Susan Sarandon.
USA, 1992.
[The true story
of two parents
of a child with
adrenoleukodystrophy -
X-linked disease
- who discover a
diet therapy].
Tom
Vaughan
(Director). Extraordinary
Measures.
With Harrison
Ford, Brendan
Fraser. USA,
2010.
[The story,
inspired by
reality, of
the discovery
of a cure for
Pompe disease (Glycogenosis
Type II)].
Andrew Niccol
(Director). Gattaca.
With Ethan
Hawke, Uma
Thurman. USA,
1997.
["There is no
gene for the
human spirit"].
***
Laboratory
Lab 1 - Data
Banks
Lab 2 - Gene Structure - Lab Exercise
Lab 3 - PCR Primer - Example
Article (MTHFR) - Example Article [COVID-19] - In-Silico PCR
Lab 4 - Data
Analysis - Statistical Analysis
software
JMP Student Edition for Macintosh and
Windows - University of Bologna is licensed
Lab 5 - Documentary
DNA